According to the CDC data and reports:
- Heart disease, cancer, and accidents (unintentional injuries) are the top three leading causes of death in the United States.
- In 2022, the U.S. had nearly 108,000 drug overdose deaths.
- In 2021, the top states for the number of drug poisoning deaths were California, Florida, and New York. However, the states that had the most drug poisoning deaths per 100,000 people were West Virginia, the District of Columbia, and Kentucky.
- According to the U.S. Centers for Disease Control and Prevention, between January 21, 2020 and January 9, 2022, there were 59 million cases of COVID-19 in the United States and the virus had claimed 834,000 lives.
- The number of U.S. deaths by firearms is higher than the number of Americans killed in motor vehicle crashes.
Major causes of death
Odds of dying from accidental injuries
The chart below shows the likelihood, or odds, of dying as a result of a specific type of accident. The odds of dying over a one-year period are based on the U.S. population as a whole, not on participants in any particular activity or on how dangerous that activity may be. For example, more people are killed in auto accidents than in motorcycle accidents or airplane crashes, not because riding a motorcycle or traveling in an airplane is more or less dangerous, but because far more people travel by car.
The opioid crisis
Additional Resources
National Highway Traffic Safety Administration (NHTSA) Fatal Crash Statistics
World Health Organization (WHO) COVID-19 Numbers at a Glance (scroll to middle of page)
Centers for Disease Control and Prevention (CDC) COVID Data Tracker
National Center for Health Statistics, Mortality in the United States
CDC, National Center for Health Statistics Firearm Mortality by State
National Vital Statistics System, Provisional Life Expectancy Estimates for 2021




